Research

Research

 

HOPE research provides academic expertise in the following areas:

  • Health Economics and Outcomes Research (HEOR)
  • Decision analysis
  • Economic modeling
  • Epidemiology
  • Biostatistics
  • Health policy
  • Qualitative research

We design and execute HEOR analyses alongside prospective clinical trials, and perform retrospective analyses of major claims databases utilizing modern tools such as R, SAS, SQL, and others.  Our analysts are seasoned specialists in budget impact and cost-effectiveness modeling using Excel/VBA, TreeAge, and R/Shiny.

We collaborate with scientists, clinicians, and stakeholders from industry, health plans, and academia to answer the most pressing questions about healthcare value today.  Our research is published in leading scientific journals as well as presented at national and international conferences.

Current areas of research focus include:

  • Aging and dementia
  • Diabetes
  • Depression
  • Ocular disease, including glaucoma, diabetic retinopathy, and cataracts
  • Infectious diseases and vaccine education programs
  • Blood products, including plasma and platelet technologies
  • Preterm birth

Current research partners include:

  • Thomas Jefferson University
  • Wills Eye Hospital
  • University of Connecticut
  • Johns Hopkins University
  • Drexel University
  • Brown University
  • University of Rochester Medical Center
  • GlaxoSmithKline
  • Cerus Corporation
  • Rutgers University Biostatistics & Epidemiology Services (RUBIES)

Among our partners is Rutgers University Biostatistics & Epidemiology Services (RUBIES).  RUBIES is a center within Rutgers Biomedical and Health Sciences and the Rutgers School of Public Health that provides statistical support, including design, programming, data management, and data analysis. RUBIES is a strategic partner of HOPE that provides advisement and analytical support from biostatistics faculty and analysts seasoned in working with healthcare data from primary sources (e.g., prospective studies) as well as secondary sources (e.g., large claims or medical record datasets). HOPE partners with RUBIES to conduct outcomes studies and, in turn, HOPE supports RUBIES by providing scientific support for research or models examining the cost or cost effectiveness of medical interventions.

Recent Publications

 

HOPE Research Publications, Peer-Reviewed

  • Pizzi LT, Onukghwa E, Alawmarwi H, Corey R, and Murray J. Competencies for New Professionals in Health Economics and Outcomes Research: The ISPOR Health Economics and Outcomes Research Competencies Framework™. Invited submission to Value in Health; accepted 04/2020 and awaiting publication.
  • Yuan J and Pizzi LT. Value-Based Payment Models Involving Pharmaceutical Services. Book chapter in: The Remington: The Science and Practice of Pharmacy. Accepted 03/2020 and awaiting final publication.
  • Gerlach JA, Snow B, Prioli KM, Vertsman R, Patterson J, Pizzi LT. An Analysis of Multi-Stakeholder Engagement in the Public Comments of ICER Draft Evidence Reports. Manuscript accepted by American Health and Drug Benefits; pending publication.
  • Hark LA, Myers JS, Ines A, Jiang A, Rahmatnejad K, Zhan T, Leiby BE, Hegarty S, Fudemberg SJ, Mantravadi AV, Waisbourd M, Henderer JD, Burns C, Divers M, Molineaux J, Pizzi LT, Murchison AP, Saaddine J, Pasquale LR, Haller JA, Katz LJ.  Philadelphia Telemedicine Glaucoma Detection and Follow-up Study: confirmation between eye screening and comprehensive eye examination diagnoses.  Br J Ophthalmol.  2019;103(12):1820-1826. doi: 10.1136/bjophthalmol-2018-313451.
  • Schafer JJ, McRae J, Prioli KM, Fields Harris L, McCoy M, Cannon-Dang E, Pizzi LT.  Exploring beliefs about pneumococcal vaccination in a predominantly older African American population:  the Pharmacists’ Pneumonia Prevention Program (PPPP).  Ethn Health.  2018 Sep 3:1-15.  doi: 10.1080/13557858.2018.1514450.
  • Prioli KM, Herman JH, Katz-Karp J, Lyons NM, Chrebtow V, Pizzi LT. Economic Implications of Pathogen Reduced and Bacterially Tested Platelet Components: A US Hospital Budget Impact Model. Appl Health Econ Health Policy.  2018;16(6):889-899.  doi: 10.1007/s40258-018-0409-3.
  • Nightingale G, Pizzi LT, Barlow A, Barlow B, Jacisin T, McGuire M, Swartz K, Chapman A. The prevalence of major drug-drug interactions in older adults with cancer and the role of clinical decision support software. Journal of Geriatric Oncology.  2018;9(5):526-533. doi: 10.1016/j.jgo.2018.02.001.
  • Pizzi LT, Waisbourd M, Hark L, Sembhi H, Lee P, Crews JE, Saaddine JB, Steele D, Katz LJ. Costs of a community-based glaucoma detection programme: analysis of the Philadelphia Glaucoma Detection and Treatment Project. British Journal of Ophthalmology 2018 Feb 1;102(2):225-32.
  • Padidam S, Wisner D, Kenney B, Peterson J, Pizzi L, Leiby BE, Hark L, Bailey R, Wills Cataract Research Group. Cataract Surgery Cancellations: An Analysis of Financial and Resident Training Implications at a Major Eye Institution. Journal of Academic Ophthalmology 2018 Jan;10(01):e1-4.
  • Pizzi LT, Prioli KM, Fields Harris L, Cannon-Dang E, Marthol-Clark M, Alcusky M, McCoy M, Schafer JJ. Knowledge, Activation, and Costs of the Pharmacists’ Pneumonia Prevention Program (PPPP): A Novel Senior Center Model to Promote Vaccination. Annals of Pharmacotherapy. 2017 Nov 1:1060028017745566. Featured in: Pizzi LT. Novel approach to promote vaccination highly successful. PharmacoEconomics & Outcomes News 2017;793:22-16.
  • Hark LA, Katz LJ, Myers JS, Waisbourd M, Johnson D, Pizzi LT, Leiby BE, Fudemberg SJ, Mantravadi AV, Henderer JD, Zhan T. Philadelphia Telemedicine Glaucoma Detection and Follow-up Study: Methods and Screening Results. American Journal of Ophthalmology 2017 Sep 1;181:114-24.
  • Prioli KM, Pizzi LT, Kash KM, Newberg AB, Morlino AM, Matthews MJ, Monti DA. Costs and effectiveness of mindfulness-based art therapy versus standard breast cancer support group for women with cancer. American Health & Drug Benefits 2017 Sep;10(6):288.
  • Nightingale G, Hajjar E, Pizzi LT, Wang M, Pigott E, Doherty S, Prioli KM, Swartz K, Chapman AE. Implementing a pharmacist-led, individualized medication assessment and planning (iMAP) intervention to reduce medication related problems among older adults with cancer. Journal of Geriatric Oncology 2017 Jul 1;8(4):296-302.
  • Murchison AP, Hark L, Pizzi LT, Dai Y, Mayro EL, Storey PP, Leiby BE, Haller JA. Non-adherence to eye care in people with diabetes. BMJ Open Diabetes Research and Care. 2017;5(1):e000333.

Research Podium or Poster Presentations, Peer-Reviewed

  • Pizzi LT, Leiby BE, Chu D, Gower EW, Ailani H, Shovlin JP, Prioli KM, Shukla S, Patterson BJ, Rausch D, Buck PO, Murchison AP.  Prospective Multicenter Observational Cohort Study to Assess the Burden of Herpes Zoster Disease in the Eye: Baseline Results of Initial Patients.  Poster presentation at the annual IDWeek conference (virtual), October 21-25, 2020.
  • Bell K, Shukla S, Waycaster C, Boyd M, Nadler E, Chao J, Ellis C, Saba NF. Real-World Evidence-based Patient Profiles and Treatment Patterns Among Patients with Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck (R/M HNSCC) from 2016-2019. Poster presentation at the annual AMCP Nexus (virtual), October 19-21, 2020.
  • Prioli KM, Herman JH, Pizzi LT.  Costs and Reimbursements for Bacterial Risk Control Strategies for Platelets:  Results from a Hospital Budget Impact Model.  Poster presentation at the AABB annual meeting (virtual), October 4, 2020.
  • Pizzi LT, Prioli KM, Babcock ZR, McAbee-Sevick H, Wakefield D, Fortinsky RH.  Cost of Delivering a Home-Based Behavioral Intervention for Persons with Dementia and their Caregivers Through the Connecticut Home Care Program for Elders.  Poster presentation at the annual Alzheimer’s Association International Conference (virtual), July 2020.
  • Yuan J, Prioli KM, Hark LA, Abersone I, Myers J, Katz LJ, Pizzi LT. Direct Costs Experienced by those in a Patient Navigator Program Versus Usual Care: Results from the Philadelphia Telemedicine Glaucoma Detection and Follow-Up Study (PTGD). Poster presentation at the 25th Annual International Meeting of the International Society for Pharmacoeconomics and Outcomes Research, Orlando, Florida, May 2020.
  • Babcock ZR, Prioli KM, Fortinsky R, McAbee-Sevick H, Wakefield D, Jutkowitz E, Yuan J, Pizzi LT. Cost of Delivering a Home-Based Behavioral Intervention for Persons with Dementia and their Caregivers through the Connecticut Home Care Program for Elders. Poster presentation at the 25th Annual International Meeting of the International Society for Pharmacoeconomics and Outcomes Research, Orlando, Florida, May 2020.
  • Shukla S, Babcock ZR, Chen W, Gandhi U, Jain S, Zhou R, Pizzi LT. Survey of Public Commenters on Draft Drug Therapy Evidence Reports to the Institute for Clinical and Economic Review. Poster presentation at the 25th Annual International Meeting of the International Society for Pharmacoeconomics and Outcomes Research, Orlando, Florida, May 2020.
  • Prioli KM, Abersone I, Vertsman R, Neese M, Schafer JJ, Fields Harris L, Jackson F, Cunningham R, Pizzi LT. Knowledge, Beliefs, and Activation Regarding Vaccine-Preventable Diseases: Results from the Vaccine Education through Pharmacists and Senior Centers (VEPSC) Study. Poster presentation at the 25th Annual International Meeting of the International Society for Pharmacoeconomics and Outcomes Research, Orlando, Florida, May 2020.
  • Prioli KM, Babcock ZR, Jain S, Cusumano EM, Ko R, Pizzi LT. A Model for Teaching Economic Modeling: Delivery of a Novel Economic Modeling Course. Poster presentation at the 25th Annual International Meeting of the International Society for Pharmacoeconomics and Outcomes Research, Orlando, Florida, May 2020.
  • Shah P, Yuan J, Acincigil A. Parkinson’s Disease Experience from a Patient’s Perspective: Systematic Review on Patient Reported Outcomes. Poster presentation at the 25th Annual International Meeting of the International Society for Pharmacoeconomics and Outcomes Research, Orlando, Florida, May 2020.
  • Pizzi LT, Prioli KM, Jutkowitz E, Yuan J, Gitlin LN. Tailored Activity Program (TAP) Costs: Opportunities to Streamline Delivery and Pursue Reimbursement. Symposium presentation at the 2019 Annual Scientific Meeting of the Gerontological Society of America, Austin, Texas, November 2019.
  • Prioli KM, Vertsman R, Schafer JJ, Fields Harris L, Jackson F, Pizzi LT.  Patient Knowledge about Vaccine-Preventable Diseases:  Baseline Results of the Vaccine Education through Pharmacists and Senior Center (VEPSC) Trial.  Poster presentation at the ISPOR 24th Annual International Meeting, New Orleans, LA, May 2019.
  • Lin D, Akincigil A.  The Impact of Heart Failure on Diabetes-Related Healthcare Resource Utilization and Costs in Adult Patient with Type 2 Diabetes Mellitus.  Poster presentation at the ISPOR 24th Annual International Meeting, New Orleans, LA, May 2019.
  • Ray M, Prioli KM, Jutkowitz E, Gitlin L, Rovner B, Casten R, Pizzi LT.  Impact of Behavioral Interventions for Chronic Diseases on Health Utility:  Assessment of Three Trials of Older Adults.  Poster presentation at the ISPOR 24th Annual International Meeting, New Orleans, LA, May 2019.
  • Guilfoyle JE, Akincigil A, Crystal S.  Prescription Opioid Medication Exposure Among Medicare Beneficiaries.  Poster presentation at the ISPOR 24th Annual International Meeting, New Orleans, LA, May 2019.
  • Vogenberg R, Pursel M, Bullard R, Pizzi LT.  Rethinking Engagement with Employer and Large Provider Purchasers through Atypical Value Modeling.  Issue panel presentation at the ISPOR 24th Annual International Meeting, New Orleans, LA, May 2019.
  • Mehta R, Prioli KM, Hark L, Katz LJ, Myers JS, Pizzi LT. Baseline Health Utility Scores in Subjects with Suspected Ocular Disease: An interim Analysis of the Philadelphia Telemedicine Glaucoma Detection and Follow-Up Study.  Poster presentation at the ISPOR 23rd Annual International Meeting, Baltimore, MD, May 2018.
  • Murray JF, Pizzi LT. The ISPOR HEOR Competencies Framework™: Guiding Professional Development for the field of HEOR.  Forum at the 23rd Annual Meeting of the International Society for  Pharmacoeconomics and Outcomes Research, Baltimore, MD, May 2018.
  • Dharamdasani T, Akincigil A, DiCesare J, Johnson K, Pizzi LT. Association Between Insurance Type and Level of Care in Community-Living Patients with Alzheimer’s Disease and Related Dementias.  Poster presentation at the ISPOR 23rd Annual International Meeting, Baltimore, MD, May 2018.
  • Willke R, Pizzi LT, Harris J, Ung B. Enabling ISPOR Member and Patient Advocacy Group Research Collaboration: A Volunteer Plan.  Forum at the 23rd Annual Meeting of the International Society for  Pharmacoeconomics and Outcomes Research, Baltimore, MD, May 2018.
  • Smart M, Seligman NS, Prioli KM, Gray LM, Pizzi LT. Cost-Effectiveness of Serial Cervical Length Screening to Prevent Preterm Birth Among High-Risk U.S. Women: A Decision Analysis.  Poster presentation at the ISPOR 23rd Annual International Meeting, Baltimore, MD, May 2018.
  • Prioli KM, Lyons NM, Karp JK, Herman JH, Pizzi LT. Cost and Shelf-Life Implications of Pathogen-Reduced Platelets: A Hospital Budget Impact Model.  Poster presentation at the ISPOR 23rd Annual International Meeting, Baltimore, MD, May 2018.
  • Prioli KM, Formal R, Schafer JJ, Fields Harris L, Jackson F, Vertsman R, Pizzi LT. Baseline Knowledge About Vaccines and Vaccine-Preventable Diseases Among Older Adults: Preliminary Baseline Analysis of the Vaccine Education through Pharmacists and Senior Centers (VEPSC) Study.  Poster presentation at the ISPOR 23rd Annual International Meeting, Baltimore, MD, May 2018.
  • Prioli KM, Lyons NM, Karp JK, Herman JH, Pizzi LT.  Costs and Shelf Life Implications of Pathogen-Reduced Platelets:  A Hospital Budget Impact Model.  Poster presentation at the AABB annual meeting, San Diego, CA, October 7, 2017.
  • Pizzi L, Jutkowitz E, Prioli K, Gitlin LN, Fortinsky R. COPE-CT Intervention Costs and Willingness to Pay Analysis: Interim Findings. International Association for Geriatrics and Gerontology Conference, San Francisco CA, July 2017.